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How informative is your kinetic model?: using resampling methods for model invalidation

BACKGROUND: Kinetic models can present mechanistic descriptions of molecular processes within a cell. They can be used to predict the dynamics of metabolite production, signal transduction or transcription of genes. Although there has been tremendous effort in constructing kinetic models for differe...

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Autores principales: Hasdemir, Dicle, Hoefsloot, Huub CJ, Westerhuis, Johan A, Smilde, Age K
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046068/
https://ncbi.nlm.nih.gov/pubmed/24886662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-61
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