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Validation and selection of ODE based systems biology models: how to arrive at more reliable decisions

BACKGROUND: Most ordinary differential equation (ODE) based modeling studies in systems biology involve a hold-out validation step for model validation. In this framework a pre-determined part of the data is used as validation data and, therefore it is not used for estimating the parameters of the m...

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Detaylı Bibliyografya
Yayımlandı:BMC Syst Biol
Asıl Yazarlar: Hasdemir, Dicle, Hoefsloot, Huub C.J, Smilde, Age K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493957/
https://ncbi.nlm.nih.gov/pubmed/26152206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0180-0
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