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Multidimensional mutual information methods for the analysis of covariation in multiple sequence alignments

BACKGROUND: Several methods are available for the detection of covarying positions from a multiple sequence alignment (MSA). If the MSA contains a large number of sequences, information about the proximities between residues derived from covariation maps can be sufficient to predict a protein fold....

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Detalhes bibliográficos
Main Authors: Clark, Greg W, Ackerman, Sharon H, Tillier, Elisabeth R, Gatti, Domenico L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046016/
https://ncbi.nlm.nih.gov/pubmed/24886131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-157
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