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Manganese-Induced Atypical Parkinsonism Is Associated with Altered Basal Ganglia Activity and Changes in Tissue Levels of Monoamines in the Rat

Manganese neurotoxicity is associated with motor and cognitive disturbances known as Manganism. However, the mechanisms underlying these deficits remain unknown. Here we investigated the effects of manganese intoxication on motor and non-motor parkinsonian-like deficits such as locomotor activity, m...

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Detalhes bibliográficos
Main Authors: Bouabid, Safa, Delaville, Claire, De Deurwaerdère, Philippe, Lakhdar-Ghazal, Nouria, Benazzouz, Abdelhamid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045849/
https://ncbi.nlm.nih.gov/pubmed/24896650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098952
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