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Manganese-Induced Atypical Parkinsonism Is Associated with Altered Basal Ganglia Activity and Changes in Tissue Levels of Monoamines in the Rat

Manganese neurotoxicity is associated with motor and cognitive disturbances known as Manganism. However, the mechanisms underlying these deficits remain unknown. Here we investigated the effects of manganese intoxication on motor and non-motor parkinsonian-like deficits such as locomotor activity, m...

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Autors principals: Bouabid, Safa, Delaville, Claire, De Deurwaerdère, Philippe, Lakhdar-Ghazal, Nouria, Benazzouz, Abdelhamid
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045849/
https://ncbi.nlm.nih.gov/pubmed/24896650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098952
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