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Protective Role of Glutathione Peroxidase 4 in Laser-Induced Choroidal Neovascularization in Mice

PURPOSE: To evaluate the influence of glutathione peroxidase 4 (GPx4) expression in retinal pigment epithelium (RPE)/choroid tissue using a mouse model of laser-induced choroidal neovascularization (CNV). METHODS: In this study, GPx4(+/−), GPx4(+/+), and GPx4-overexpressing transgenic mice were crea...

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Autors principals: Roggia, Murilo Felix, Imai, Hirotaka, Shiraya, Tomoyasu, Noda, Yasuo, Ueta, Takashi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045803/
https://ncbi.nlm.nih.gov/pubmed/24897344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098864
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