Transgenic Mice Showing Inflammation-Inducible Overexpression of Granulocyte Macrophage Colony-Stimulating Factor

We used the promoter of the human C-reactive protein (CRP) gene to drive inflammation-inducible overexpression of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) in transgenic mice. Transgenic mice carrying a CRP/GM-CSF fusion gene show a >150-fold increases in circulating...

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Bibliografiske detaljer
Main Authors: Burke, B., Pridmore, A., Harraghy, N., Collick, A., Brown, J., Mitchell, T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Immune-Mediated Responses and Disorders
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404575/
https://ncbi.nlm.nih.gov/pubmed/15138187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.11.3.588-598.2004
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