Transgenic Overexpression of Granulocyte Macrophage-Colony Stimulating Factor in the Lung Prevents Hyperoxic Lung Injury

Granulocyte macrophage-colony stimulating factor (GM-CSF) plays an important role in pulmonary homeostasis, with effects on both alveolar macrophages and alveolar epithelial cells. We hypothesized that overexpression of GM-CSF in the lung would protect mice from hyperoxic lung injury by limiting alv...

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Bibliographic Details
Main Authors: Paine, Robert, Wilcoxen, Steven E., Morris, Susan B., Sartori, Claudio, Baleeiro, Carlos E. O., Matthay, Michael A., Christensen, Paul J.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892382/
https://ncbi.nlm.nih.gov/pubmed/14633611
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