Design, Synthesis and Evaluation of Novel 2,5,6-Trisubstituted Benzimidazoles Targeting FtsZ as Antitubercular Agents

Filamenting temperature-sensitive protein Z (FtsZ), an essential cell division protein, is a promising target for the drug discovery of new-generation antibacterial agents against various bacterial pathogens. As a part of SAR studies on benzimidazoles, we have synthesized a library of 376 novel 2,5,...

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Hlavní autoři: Park, Bora, Awasthi, Divya, Chowdhury, Soumya R., Melief, Eduard H., Kumar, Kunal, Knudson, Susan E., Slayden, Richard A., Ojima, Iwao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045703/
https://ncbi.nlm.nih.gov/pubmed/24726304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.03.035
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