Quantification of excision repair cross complementing group 1 (ERCC1) and survival in p16-negative squamous cell head and neck cancers

PURPOSE: Multimodality treatment for squamous cell carcinoma of the head and neck (SCCHN) often involves radiation (RT) and cisplatin-based therapy. Elevated activity of DNA repair mechanisms, such as the nucleotide excision repair (NER) pathway, of which ERCC1 is a rate-limiting element, are associ...

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Hoofdauteurs: Mehra, Ranee, Zhu, Fang, Yang, Dong-Hua, Cai, Kathy Q., Weaver, JoEllen, Singh, Mahendra K., Nikonova, Anna S., Golemis, Erica A., Flieder, Douglas B., Cooper, Harry S., Lango, Miriam, Ridge, John A., Burtness, Barbara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045641/
https://ncbi.nlm.nih.gov/pubmed/24088734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0152
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