FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen.
In establishing the memory B-cell population and maintaining self-tolerance during an immune response, apoptosis mediates the removal of early, low-affinity antibody-forming cells, unselected germinal center (GC) cells, and, potentially, self-reactive B cells. To address the role of the apoptosis-si...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.25.11628 |
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