Virus-Encoded MicroRNAs Facilitate Gammaherpesvirus Latency and Pathogenesis In Vivo

Gammaherpesviruses, including Epstein-Barr virus (EBV), Kaposi sarcoma-associated herpesvirus (KSHV, or HHV-8), and murine gammaherpesvirus 68 (MHV68, γHV68, or MuHV-4), are B cell-tropic pathogens that each encode at least 12 microRNAs (miRNAs). It is predicted that these regulatory RNAs facilitate...

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Main Authors: Feldman, Emily R., Kara, Mehmet, Coleman, Carrie B., Grau, Katrina R., Oko, Lauren M., Krueger, Brian J., Renne, Rolf, van Dyk, Linda F., Tibbetts, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045068/
https://ncbi.nlm.nih.gov/pubmed/24865551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00981-14
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