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Transposon Mutagenesis of the Obligate Intracellular Pathogen Rickettsia prowazekii

Genetic analysis of Rickettsia prowazekii has been hindered by the lack of selectable markers and efficient mechanisms for generating rickettsial gene knockouts. We have addressed these problems by adapting a gene that codes for rifampin resistance for expression in R. prowazekii and by incorporatin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qin, Aiping, Tucker, Aimee M., Hines, Andria, Wood, David O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404435/
https://ncbi.nlm.nih.gov/pubmed/15128537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.5.2816-2822.2004
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