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Transposon Mutagenesis of the Obligate Intracellular Pathogen Rickettsia prowazekii

Genetic analysis of Rickettsia prowazekii has been hindered by the lack of selectable markers and efficient mechanisms for generating rickettsial gene knockouts. We have addressed these problems by adapting a gene that codes for rifampin resistance for expression in R. prowazekii and by incorporatin...

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Autors principals: Qin, Aiping, Tucker, Aimee M., Hines, Andria, Wood, David O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC404435/
https://ncbi.nlm.nih.gov/pubmed/15128537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.5.2816-2822.2004
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