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Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes

Endoplasmic reticulum (ER) stress has been implicated in a variety of cardiovascular diseases. During ER stress, disruption of the complex of protein phosphatase 1 regulatory subunit 15A and catalytic subunit of protein phosphatase 1 by the small molecule guanabenz (antihypertensive, α(2)-adrenocept...

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Autors principals: Neuber, Christiane, Uebeler, June, Schulze, Thomas, Sotoud, Hannieh, El-Armouche, Ali, Eschenhagen, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044035/
https://ncbi.nlm.nih.gov/pubmed/24892553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098893
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