Influence of a Constitutive Increase in Myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and Contraction of Mouse Heart Ventricular Myocytes

Chronic increases in myofilament Ca(2+)-sensitivity in the heart are known to alter gene expression potentially modifying Ca(2+)-homeostasis and inducing arrhythmias. We tested age-dependent effects of a chronic increase in myofilament Ca(2+)-sensitivity on induction of altered alter gene expression...

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Hlavní autoři: Puglisi, Jose L., Goldspink, Paul H., Gomes, Aldrin V., Utter, Megan S., Bers, Donald M., Solaro, R. John
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043955/
https://ncbi.nlm.nih.gov/pubmed/24480308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.01.019
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