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Transformation of Folate-Consuming Lactobacillus gasseri into a Folate Producer

Five genes essential for folate biosynthesis in Lactococcus lactis were cloned on a broad-host-range lactococcal vector and were transferred to the folate auxotroph Lactobacillus gasseri. As a result L. gasseri changed from a folate consumer to a folate producer. This principle can be used to increa...

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Autors principals: Wegkamp, Arno, Starrenburg, Marjo, de Vos, Willem M., Hugenholtz, Jeroen, Sybesma, Wilbert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC404390/
https://ncbi.nlm.nih.gov/pubmed/15128580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.5.3146-3148.2004
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