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Transformation of Verapamil by Cunninghamella blakesleeana
A filamentous fungus, Cunninghamella blakesleeana AS 3.153, was used as a microbial model of mammalian metabolism to transform verapamil, a calcium channel antagonist. The metabolites of verapamil were separated and assayed by the liquid chromatography-ion trap mass spectrometry method. After 96 h o...
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| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2004
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC404379/ https://ncbi.nlm.nih.gov/pubmed/15128524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.5.2722-2727.2004 |
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