Transformation of Verapamil by Cunninghamella blakesleeana

A filamentous fungus, Cunninghamella blakesleeana AS 3.153, was used as a microbial model of mammalian metabolism to transform verapamil, a calcium channel antagonist. The metabolites of verapamil were separated and assayed by the liquid chromatography-ion trap mass spectrometry method. After 96 h o...

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Bibliografiske detaljer
Main Authors: Sun, Lu, Huang, Hai-Hua, Liu, Lei, Zhong, Da-Fang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Mycology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC404379/
https://ncbi.nlm.nih.gov/pubmed/15128524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.5.2722-2727.2004
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