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Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region

OBJECTIVE: Tissue factor pathway inhibitor (TFPI) blocks the initiation of coagulation by inhibiting TF-activated factor VII, activated factor X, and early prothrombinase. Humans produce two 3′ splice variants, TFPIα and TFPIβ, which are differentially expressed in endothelial cells and platelets an...

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Hlavní autoři: Ellery, Paul E.R., Maroney, Susan A., Martinez, Nicholas D., Wickens, Marvin P., Mast, Alan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043743/
https://ncbi.nlm.nih.gov/pubmed/24233486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302660
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