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Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region
OBJECTIVE: Tissue factor pathway inhibitor (TFPI) blocks the initiation of coagulation by inhibiting TF-activated factor VII, activated factor X, and early prothrombinase. Humans produce two 3′ splice variants, TFPIα and TFPIβ, which are differentially expressed in endothelial cells and platelets an...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043743/ https://ncbi.nlm.nih.gov/pubmed/24233486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302660 |
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