Pharmacokinetics and Safety of Nelfinavir When Used in Combination with Zidovudine and Lamivudine in HIV-Infected Pregnant Women: Pediatric AIDS Clinical Trials Group (PACTG) Protocol 353

BACKGROUND: Combination antiretroviral regimens including nelfinavir (NFV) are commonly used in pregnancy. We studied the safety, antiviral effect, and pharmacokinetics of NFV and its M8 metabolite with two dosing regimens in combination with zidovudine (ZDV) and lamivudine (3TC) in HIV-infected pre...

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Autores principales: Bryson, Y.J., Mirochnick, M., Stek, A., Mofenson, L.M., Connor, J., Capparelli, E., Watts, D.H., Huang, S., Hughes, M.D., Kaiser, K., Purdue, L., Asfaw, Y., Keller, M., Smith, E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043374/
https://ncbi.nlm.nih.gov/pubmed/18474496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1310/hct0902-115
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