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Rapamycin is a Potent Inhibitor of Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-acetate
Aberrant activation of PI3K/Akt signaling has been implicated in the development and progression of multiple human cancers. During the process of skin tumor promotion induced by treatment with the phorbol ester TPA, activation of epidermal Akt occurs as well as several downstream effectors of Akt, i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043296/ https://ncbi.nlm.nih.gov/pubmed/21733825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0375 |
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