Cell-type-specific roles for COX-2 in UVB-induced skin cancer

In human tumors, and in mouse models, cyclooxygenase-2 (COX-2) levels are frequently correlated with tumor development/burden. In addition to intrinsic tumor cell expression, COX-2 is often present in fibroblasts, myofibroblasts and endothelial cells of the tumor microenvironment, and in infiltratin...

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Detalhes bibliográficos
Main Authors: Jiao, Jing, Mikulec, Carol, Ishikawa, Tomo-o, Magyar, Clara, Dumlao, Darren S., Dennis, Edward A., Fischer, Susan M., Herschman, Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043244/
https://ncbi.nlm.nih.gov/pubmed/24469308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu020
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