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Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase

M1 activation of macrophages promotes inflammation and immunity to intracellular pathogens, while M2 macrophage activation promotes resolution of inflammation, wound healing, and tumor growth. These divergent phenotypes are characterized, in part, by the expression of iNOS and arginase I (Arg1) in M...

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Detalhes bibliográficos
Main Authors: Sharda, Daniel R., Yu, Shan, Ray, Manujendra, Squadrito, Mario Leonardo, De Palma, Michele, Wynn, Thomas A., Morris, Sidney M., Hankey, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042865/
https://ncbi.nlm.nih.gov/pubmed/21810604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003460
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