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Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain

BACKGROUND: The Ron receptor tyrosine kinase (RTK) has been implicated in the progression of a number of carcinomas, thus understanding the regulatory mechanisms governing its activity is of potential therapeutic significance. A critical role for the juxtamembrane domain in regulating RTK activity i...

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Autors principals: Wang, Xin, Yennawar, Neela, Hankey, Pamela A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021555/
https://ncbi.nlm.nih.gov/pubmed/24739671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-28
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