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Simple, Low-Cost Molecular Assays for TR(34)/L98H Mutations in the cyp51A Gene for Rapid Detection of Triazole-Resistant Aspergillus fumigatus Isolates

Simple, low-cost PCR/PCR-restriction fragment length polymorphism (RFLP) assays targeting cyp51A promoter and codon 98 regions were developed for the detection of triazole-resistant Aspergillus fumigatus strains carrying TR(34)/L98H mutations. The assays were evaluated using 40 itraconazole-suscepti...

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Detalhes bibliográficos
Main Authors: Ahmad, Suhail, Khan, Ziauddin, Hagen, Ferry, Meis, Jacques F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042779/
https://ncbi.nlm.nih.gov/pubmed/24719446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00408-14
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