Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis

Pneumonia is a major cause of mortality worldwide and a serious problem in critical care medicine, but the immunophysiological processes that confer either protection or morbidity are not completely understood. We show that in response to lung infection, B1a B cells migrate from the pleural space to...

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Hauptverfasser: Weber, Georg F., Chousterman, Benjamin G., Hilgendorf, Ingo, Robbins, Clinton S., Theurl, Igor, Gerhardt, Louisa M.S., Iwamoto, Yoshiko, Quach, Tam D., Ali, Muhammad, Chen, John W., Rothstein, Thomas L., Nahrendorf, Matthias, Weissleder, Ralph, Swirski, Filip K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042649/
https://ncbi.nlm.nih.gov/pubmed/24821911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131471
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