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10-million-years AGO: Argonaute on chromatin in yeast and human, a conserved mode of action?

Whereas in yeast the function and mode of action of nuclear RNAi are well documented, mammalian nuclear RNAi is a matter of debates. Several papers support a role for nuclear Argonaute in alternative splicing. However, the molecular mechanism remains elusive. Here, we discuss the human nuclear RNAi...

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Autori principali: Harel-Bellan, Annick, Ameyar-Zazoua, Maya, Rachez, Christophe, Muchardt, Christian, Batsché, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042589/
https://ncbi.nlm.nih.gov/pubmed/23584094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.24582
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