Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage.

Focal brain ischemia is the most common event leading to stroke in humans. To understand the molecular mechanisms associated with brain ischemia, we applied the technique of mRNA differential display and isolated a gene that encodes a recently discovered peptide, adrenomedullin (AM), which is a memb...

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Main Authors: Wang, X, Yue, T L, Barone, F C, White, R F, Clark, R K, Willette, R N, Sulpizio, A C, Aiyar, N V, Ruffolo, R R, Feuerstein, G Z
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC40425/
https://ncbi.nlm.nih.gov/pubmed/8524787
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