Generation of neural progenitor cells by chemical cocktails and hypoxia

Neural progenitor cells (NPCs) can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts by a chemical cocktail, namely VCR (V, VPA, an inhibitor of HDACs; C, CHIR99021, an inhibitor of GSK-3 kinases and R, Repsox, an inhibitor o...

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Bibliografiske detaljer
Main Authors: Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042166/
https://ncbi.nlm.nih.gov/pubmed/24638034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.32
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