Generation of neural progenitor cells by chemical cocktails and hypoxia

Neural progenitor cells (NPCs) can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts by a chemical cocktail, namely VCR (V, VPA, an inhibitor of HDACs; C, CHIR99021, an inhibitor of GSK-3 kinases and R, Repsox, an inhibitor o...

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Detalhes bibliográficos
Main Authors: Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042166/
https://ncbi.nlm.nih.gov/pubmed/24638034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.32
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