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P2Y(2) receptors regulate osteoblast mechanosensitivity during fluid flow
Mechanical stimulation of osteoblasts activates many cellular mechanisms including the release of ATP. Binding of ATP to purinergic receptors is key to load-induced osteogenesis. Osteoblasts also respond to fluid shear stress (FSS) with increased actin stress fiber formation (ASFF) that we postulate...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4042092/ https://ncbi.nlm.nih.gov/pubmed/24696143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00254.2013 |
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