P2Y(2) receptors regulate osteoblast mechanosensitivity during fluid flow

Mechanical stimulation of osteoblasts activates many cellular mechanisms including the release of ATP. Binding of ATP to purinergic receptors is key to load-induced osteogenesis. Osteoblasts also respond to fluid shear stress (FSS) with increased actin stress fiber formation (ASFF) that we postulate...

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Bibliografiske detaljer
Main Authors: Gardinier, Joseph, Yang, Weidong, Madden, Gregory R., Kronbergs, Andris, Gangadharan, Vimal, Adams, Elizabeth, Czymmek, Kirk, Duncan, Randall L.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042092/
https://ncbi.nlm.nih.gov/pubmed/24696143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00254.2013
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