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Novel early response genes in osteoblasts exposed to dynamic fluid flow

Cyclic mechanical loads applied to the skeleton from habitual physical activity result in increased bone formation. These loads lead to dynamic pressure gradients and oscillatory flow of bone interstitial fluid, which, in turn, exposes cells resident in the bony matrix to oscillatory fluid shear str...

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Autori principali: Shivaram, Giridhar M., Kim, Chi Hyun, Batra, Nikhil N., Yang, Wuchen, Harris, Stephen E., Jacobs, Christopher R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society Publishing 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944389/
https://ncbi.nlm.nih.gov/pubmed/20047941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsta.2009.0231
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