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Integrins and cadherins as therapeutic targets in fibrosis
Fibrosis is the excessive deposition of extracellular matrix proteins into tissues leading to scar formation, disruption of normal tissue architecture and organ failure. Despite the large clinical impact of fibrosis, treatment options are limited. Adhesion molecules, in particular αvβ6 and α3β1 inte...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2014
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4042084/ https://ncbi.nlm.nih.gov/pubmed/24917820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00131 |
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