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SGK3 Is an Androgen-Inducible Kinase Promoting Prostate Cancer Cell Proliferation Through Activation of p70 S6 Kinase and Up-Regulation of Cyclin D1

Both androgen and phosphatidylinositol 3-kinase (PI3K) signaling are critical for cell proliferation of androgen receptor (AR)–positive prostate cancer cells, but the underlying mechanisms are still not fully understood. Here we report that serum- and glucocorticoid-inducible kinase 3 (SGK3), a Ser/...

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Main Authors: Wang, Yuanzhong, Zhou, Dujin, Chen, Shiuan
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042072/
https://ncbi.nlm.nih.gov/pubmed/24739041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1339
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