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Dose–Response Cocaine Pharmacokinetics and Metabolite Profile Following Intravenous Administration and Arterial Sampling in Unanesthetized, Freely Moving Male Rats

Despite the wealth of experimental data on cocaine abuse, there are no published dose–response pharmacokinetic studies with bolus IV cocaine injection in the male rat. The present study examined the pharmacokinetics of arterial plasma concentrations of cocaine and metabolite profile [benzoylecgonine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Booze, R. M., Lehner, A. F., Wallace, D. R., Welch, M. A., Mactutus, C. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041984/
https://ncbi.nlm.nih.gov/pubmed/9088006
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