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MyD88 mediates the decision to die by apoptosis or necroptosis after UV irradiation

UV irradiation-induced cellular damage is classically associated with apoptosis and is known to result in systemic immunosuppression. How the decision to undergo apoptosis is made following UV is not fully understood. We hypothesize that a central mediator of TLR signaling, MyD88, determines cell fa...

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Detalhes bibliográficos
Main Authors: Harberts, Erin, Fishelevich, Rita, Liu, Juan, Atamas, Sergei P, Gaspari, Anthony A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041851/
https://ncbi.nlm.nih.gov/pubmed/24048771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425913501706
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