Heat Shock Protein-70 (Hsp-70) Suppresses Paraquat-Induced Neurodegeneration by Inhibiting JNK and Caspase-3 Activation in Drosophila Model of Parkinson's Disease

Parkinson's disease (PD) is one of the most common neurodegenerative disorders with limited clinical interventions. A number of epidemiological as well as case-control studies have revealed an association between pesticide exposure, especially of paraquat (PQ) and occurrence of PD. Hsp70, a mol...

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Autors principals: Shukla, Arvind Kumar, Pragya, Prakash, Chaouhan, Hitesh Singh, Tiwari, Anand Krishna, Patel, Devendra Kumar, Abdin, Malik Zainul, Chowdhuri, Debapratim Kar
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041817/
https://ncbi.nlm.nih.gov/pubmed/24887138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098886
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