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Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans
Adenosine deaminases that act on RNA (ADAR) are a class of enzymes that catalyze the conversion of adenosine to inosine in RNA. Since inosine is read as guanosine ADAR activity formally introduces A-to-G point mutations. Re-addressing ADAR activity toward new targets in an RNA-dependent manner is a...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041445/ https://ncbi.nlm.nih.gov/pubmed/24744243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku272 |
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