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Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding
Adenosine deaminases that act on RNA (ADARs) catalyze adenosine to inosine conversion in RNA that is largely double stranded. Human ADAR2 (hADAR2) contains two double-stranded RNA binding motifs (dsRBMs), separated by a 90-amino acid linker, and these are followed by the C-terminal catalytic domain....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright 2004 by RNA Society
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370643/ https://ncbi.nlm.nih.gov/pubmed/15383678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7920904 |
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