Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics

The Staphylococcus aureus genome contains three toxin–antitoxin modules, including one mazEF module, SamazEF. Using an on-column separation protocol we are able to obtain large amounts of wild-type SaMazF toxin. The protein is well-folded and highly resistant against thermal unfolding but aggregates...

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Autors principals: Zorzini, Valentina, Buts, Lieven, Sleutel, Mike, Garcia-Pino, Abel, Talavera, Ariel, Haesaerts, Sarah, Greve, Henri De, Cheung, Ambrose, van Nuland, Nico A. J., Loris, Remy
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041440/
https://ncbi.nlm.nih.gov/pubmed/24748664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku266
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