Crystal structure of a 4-thiouridine synthetase–RNA complex reveals specificity of tRNA U8 modification

In prokaryotes and archaea transfer ribonucleic acid (tRNA) stability as well as cellular UV protection relies on the post-transcriptional modification of uracil at position 8 (U8) of tRNAs by the 4-thiouridine synthetase ThiI. Here, we report three crystal structures of ThiI from Thermotoga maritim...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Neumann, Piotr, Lakomek, Kristina, Naumann, Peter-Thomas, Erwin, Whitney M., Lauhon, Charles T., Ficner, Ralf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Structural Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041423/
https://ncbi.nlm.nih.gov/pubmed/24705700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku249
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg