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Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

The fetal/neonatal hematopoietic system must generate enough blood cells to meet the demands of rapid growth. This unique challenge might underlie the high incidence of thrombocytopenia among preterm neonates. In this study, neonatal platelet production and turnover were investigated in newborn mice...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Zhi-Jian, Hoffmeister, Karin M., Hu, Zhongbo, Mager, Donald E., Ait-Oudhia, Sihem, Debrincat, Marlyse A., Pleines, Irina, Josefsson, Emma C., Kile, Benjamin T., Italiano, Joseph, Ramsey, Haley, Grozovsky, Renata, Veng-Pedersen, Peter, Chavda, Chaitanya, Sola-Visner, Martha
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041172/
https://ncbi.nlm.nih.gov/pubmed/24599546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-06-508200
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