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A model reduction method for biochemical reaction networks

BACKGROUND: In this paper we propose a model reduction method for biochemical reaction networks governed by a variety of reversible and irreversible enzyme kinetic rate laws, including reversible Michaelis-Menten and Hill kinetics. The method proceeds by a stepwise reduction in the number of complex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rao, Shodhan, der Schaft, Arjan van, Eunen, Karen van, Bakker, Barbara M, Jayawardhana, Bayu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041147/
https://ncbi.nlm.nih.gov/pubmed/24885656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-52
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