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Exact model reduction of combinatorial reaction networks

BACKGROUND: Receptors and scaffold proteins usually possess a high number of distinct binding domains inducing the formation of large multiprotein signaling complexes. Due to combinatorial reasons the number of distinguishable species grows exponentially with the number of binding domains and can ea...

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Autors principals: Conzelmann, Holger, Fey, Dirk, Gilles, Ernst D
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570670/
https://ncbi.nlm.nih.gov/pubmed/18755034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-2-78
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