Removal of Polysialylated Neural Cell Adhesion Molecule Increases Morphine Analgesia and Interferes with Tolerance in Mice

Neurons that express high levels of polysialylated neural cell adhesion molecule (PSANCAM) in adult spinal substantia gelatinosa also express the μ-opioid receptor. While PSA removal from NCAM by spinal intrathecal injection of endoneuraminidase-N (endo-N) did not detectably change opioid receptor e...

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Main Authors: El Maarouf, Abderrahman, Kolesnikov, Yuri, Pasternak, Gavril, Rutishauser, Urs
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041115/
https://ncbi.nlm.nih.gov/pubmed/21704981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.06.021
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