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Blocking interaction of viral gp120 and CD4-expressing T cells by single-stranded DNA aptamers
To investigate the potential clinical application of aptamers to prevention of HIV infection, single- stranded DNA (ssDNA) aptamers specific for CD4 were developed using the systematic evolution of ligands by exponential enrichment approach and next generation sequencing. In contrast to RNA-based ap...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041034/ https://ncbi.nlm.nih.gov/pubmed/24661998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.03.008 |
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