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Population-Genetic Inference from Pooled-Sequencing Data
Although pooled-population sequencing has become a widely used approach for estimating allele frequencies, most work has proceeded in the absence of a proper statistical framework. We introduce a self-sufficient, closed-form, maximum-likelihood estimator for allele frequencies that accounts for erro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040993/ https://ncbi.nlm.nih.gov/pubmed/24787620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evu085 |
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