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Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage

Toxicity from radiation therapy is a grave problem for cancer patients. We hypothesized that some cases of toxicity are associated with abnormal transcriptional responses to radiation. We used microarrays to measure responses to ionizing and UV radiation in lymphoblastoid cells derived from 14 patie...

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Detalhes bibliográficos
Main Authors: Rieger, Kerri E., Hong, Wan-Jen, Tusher, Virginia Goss, Tang, Jean, Tibshirani, Robert, Chu, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404097/
https://ncbi.nlm.nih.gov/pubmed/15096622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307761101
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